Article

High Cellular Uptake Gene Delivery Platform with Chitosan and L-arginine Complex for Cancer Treatment

2022-02-25

Abstract excerpt

Gene therapy outperforms chemotherapy in limiting the harm to human body. A major impediment to the progress of gene therapy is a lack of proper carriers. Chitosan, derived from shellfish, is a desirable candidate for nucleic acid delivery because of its outstanding biodegradability and biocompatibility. However, previous works show that chitosan has poor cell membrane permeability. In this study, we synthesize a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5dcb7281-e821-5a87-ac41-1e5f88d83d82
DOI: 10.1101/2022.02.22.481395

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

High Cellular Uptake Gene Delivery Platform with Chitosan and L-arginine Complex for Cancer TreatmentDOI 10.1101/2022.02.22.481395Read

Synthesis, characterization, and molecular docking analysis of a novel nanocarrier for gene therapy in renal cell carcinomaSemantic proximity Read

Chitosan in Modern Pharmacotherapy: From Drug Encapsulation to Targeted Delivery SystemsSemantic proximity Read

Application of Marine-Based Gold Nanomaterials in Cancer Therapy: A Mini-ReviewSemantic proximity Read

Efficient mRNA Delivery <i>In Vitro</i> and <i>In Vivo</i> Using a Polycharged Biodegradable NanomaterialSemantic proximity Read

Mutation of arginine residues to avoid non-specific cellular uptakes for hepatitis B virus core particles.Semantic proximity Read

Engineering siRNA-loaded and RGDfC-targeted selenium nanoparticles for highly efficient silencing of DCBLD2 gene for colorectal cancer treatmentSemantic proximity Read

Gold/cationic polymer nano-scaffolds mediated transfection for non-viral gene delivery systemSemantic proximity Read

Development of a nanoparticle that releases nucleic acids in response to a mitochondrial environment.Semantic proximity Read

Chitosan-tripolyphosphate nanoparticles as a novel vehicle for DNA vaccine delivery: combatting Aeromonas hydrophila in zebrafishSemantic proximity Read

Human-derived NLS enhance the gene transfer efficiency of chitosanSemantic proximity Read

AS1411-targeted graphene oxide nano-drug delivery system for chemo-photothermal therapy of cervical cancerSemantic proximity Read

Dual delivery of nucleic acids and PEGylated-bisphosphonates <i>via</i> calcium phosphate nanoparticlesSemantic proximity Read