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Article

Novel human SR-BI antibodies prevent infection and dissemination of HCV in vitro and in humanized mice.

Journal of hepatology - 1 Jul 2012

Lacek Krzysztof, Vercauteren Koen, Grzyb Katarzyna, Naddeo Mariarosaria, Verhoye Lieven, Słowikowski Marek Patryk, Fafi-Kremer Samira, Patel Arvind H, Baumert Thomas F, Folgori Antonella, Leroux-Roels Geert, Cortese Riccardo, Meuleman Philip, Nicosia Alfredo

Abstract excerpt

BACKGROUND & AIMS: Hepatitis C virus (HCV)-induced end-stage liver disease is currently the major indication for liver transplantation in the Western world. After transplantation, the donor liver almost inevitably becomes infected by the circulating virus and disease progression is accelerated in immune suppressed transplant patients. The current standard therapy, based on pegylated interferon and ribavirin,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22414763
DOI: 10.1016/j.jhep.2012.02.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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