New candidate gene mutation in astrocytoma with seizures

Abstract excerpt

<title>Abstract</title> <p>Patients with astrocytomas frequently experience seizures. Patients with glioma who had preoperative epilepsy had significantly longer survival than those without seizures. However, the preoperative risk factors for seizures remain unclear. Moreover, previous studies have suggested that tumor genomics, rather than tumor location, mass effect, or tumor volume, plays a critical role in se...

Topics

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• Aged
• Astrocytoma
• Brain Neoplasms
• Exome Sequencing
• Genetic Association Studies
• Genetic Predisposition to Disease
• Isocitrate Dehydrogenase
• Seizures

Identifiers and source

Literature Corpus work

5dbf0265-b517-5a65-bbfa-c5b11e63086c

DOI

10.21203/rs.3.rs-5980159/v1