Article
Integrated genotype-phenotype analysis of long-term epilepsy-associated ganglioglioma.
Brain pathology (Zurich, Switzerland) - 1 Jan 2022
Wang Yujiao, Wang Leiming, Blümcke Ingmar, Zhang Weiwei, Fu Yongjuan, Shan Yongzhi, Piao Yueshan, Zhao Guoguang
Abstract excerpt
The BRAF p.V600E mutation is the most common genetic alteration in ganglioglioma (GG). Herein, we collected a consecutive series of 30 GG specimens from Xuanwu Hospital in order to corroborate the genetic landscape and genotype-phenotype correlation of this enigmatic and often difficult-to-classify epilepsy-associated brain tumor entity. All specimens with histopathologically confirmed lesions were submitted to...
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