Article

Tumors Located in the Brain Impair the Frequency and Phenotype of Dendritic Cells in Blood and Tumor

2025-11-07

Abstract excerpt

<h4>Background</h4> Professional antigen-presenting dendritic cells (DC) are critical for anti-tumor immune responses, yet patients with glioblastoma, an aggressive primary brain tumor that responds poorly to current investigational immunotherapies, appear to be deficient in DC. The extent of this deficiency, the specific DC subsets affected, and the causative mechanisms remain undefined. Furthermore, DCs in othe...

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Literature Corpus work: 5d96625f-7210-5804-9853-8fd85e8bbe99
DOI: 10.1101/2025.11.05.686441

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