Article

Characterization of the intraspecies chimeric mouse brain at embryonic day 12.5

2025-04-02

Abstract excerpt

Incidence of neurodegenerative diseases such as Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis have increased dramatically as life expectancy at birth has risen year-over-year and the population ages. Neurological changes within the central nervous system, specifically the brain, include cell loss and deterioration that impact motor function, memory, executive function, and mood. Availab...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5d5171a0-4b99-546e-b256-9561b8b33318
DOI: 10.1101/2025.03.31.646380

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Characterization of the intraspecies chimeric mouse brain at embryonic day 12.5DOI 10.1101/2025.03.31.646380Read

Direct analysis of brain phenotypes via neural blastocyst complementation.Semantic proximity Read

Human-Mouse Chimeric Brain Models to Study Human Glial-Neuronal and Macroglial-Microglial InteractionsSemantic proximity Read

Building functional circuits in multispecies brainsSemantic proximity Read

Improved Method for Efficient Generation of Functional Neurons from Murine Neural Progenitor Cells.Semantic proximity Read

Neural differentiation and incorporation of bone marrow-derived multipotent adult progenitor cells after single cell transplantation into blastocyst stage mouse embryos.Semantic proximity Read

Long-lasting structural and functional maturation in transplanted human neurons reprogrammed from glial progenitor cellsSemantic proximity Read

A Simple Differentiation Protocol for Generation of Induced Pluripotent Stem Cell-Derived Basal Forebrain-Like Cholinergic Neurons for Alzheimer’s Disease and Frontotemporal Dementia Disease ModelingSemantic proximity Read

A Simple Differentiation Protocol for Generation of Induced Pluripotent Stem Cell-derived Basal Forebrain Cholinergic Neurons for Alzheimer’s Disease and Frontotemporal Dementia Disease ModelingSemantic proximity Read

Adult olfactory bulb neural precursor cell grafts provide temporary protection from motor neuron degeneration, improve motor function, and extend survival in amyotrophic lateral sclerosis mice.Semantic proximity Read

Efficient Derivation of Multipotent Neural Stem/Progenitor Cells from Non-Human Primate Embryonic Stem CellsSemantic proximity Read

Stable fusion of bone marrow-derived cells with Purkinje neurons enables long-term nuclear integration and neuronal repairSemantic proximity Read

Human neural stem cell transplantation improves cognition in a murine model of Alzheimer’s diseaseSemantic proximity Read