Article
Neural differentiation and incorporation of bone marrow-derived multipotent adult progenitor cells after single cell transplantation into blastocyst stage mouse embryos.
Cell transplantation - 1 Jan 2003
Keene C Dirk, Ortiz-Gonzalez Xilma R, Jiang Yuehua, Largaespada David A, Verfaillie Catherine M, Low Walter C
Abstract excerpt
Previously we reported the characterization of multipotent adult progenitor cells (MAPCs) isolated from the bone marrow of rodents. In that study, single murine MAPCs derived from ROSA-26, beta-galactosidase (beta-Gal)-positive transgenic mice were injected into E3.5 C57/B16 mouse blastocysts. The resultant chimeric blastocysts were then implanted into pseudopregnant females and were allowed to develop naturally...
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