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MAVS Protein Is Attenuated by Rotavirus Nonstructural Protein 1

18 Mar 2014

Abstract excerpt

Rotavirus is the single, most important agent of infantile gastroenteritis in many animal species, including humans. In developing countries, rotavirus infection attributes approximately 500,000 deaths annually. Like other viruses it establishes an intimate and complex interaction with the host cell to counteract the antiviral responses elicited by the cell. Among various pattern recognition receptors (PAMPs) of...

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PMID: 24643253
DOI: 10.1371/journal.pone.0092126

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