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A recombinant murine rotavirus with Nano-Luciferase expression reveals tissue tropism, replication dynamics, and virus transmission

2022-04-12

Abstract excerpt

<h4>ABSTRACT</h4> Rotaviruses (RVs) are one of the main causes of severe gastroenteritis, diarrhea, and death in children and young animals. Although suckling mice prove to be highly useful small animal models of RV infection and pathogenesis, direct visualization tools are lacking to track the temporal dynamics of RV replication and transmissibility in vivo . Here, we report the generation of the first recombin...

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Literature Corpus work
5b8886f2-8c6b-55c9-bfc3-e1af9ea383df
DOI
10.1101/2022.04.12.488073
Open publication

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A recombinant murine rotavirus with Nano-Luciferase expression reveals tissue tropism, replication dynamics, and virus transmissionDOI 10.1101/2022.04.12.488073
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