Article
Studies of the role for NSP4 in the pathogenesis of homologous murine rotavirus diarrhea.
The Journal of infectious diseases - 1 Feb 1998
Angel J, Tang B, Feng N, Greenberg H B, Bass D
Abstract excerpt
A rotavirus (RV) nonstructural protein, NSP4, has recently been proposed to function as an enterotoxin in the pathogenesis of RV diarrhea. The role of NSP4 in the pathogenesis of RV diarrhea was examined by infecting cystic fibrosis transmembrane conductance regulator (CFTR) knockout mice with virulent murine RV and by comparing deduced amino acid sequences of RV gene 10 encoding NSP4 from three distinct sets of...
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