Article

Pan-cancer study on transition of signaling systems from primary to metastatic tumors

2024-11-12

Abstract excerpt

Metastatic progression is responsible for the majority of cancer-related deaths. A better understanding of the underlying molecular mechanisms driving metastasis therefore remains of utmost importance. Here we take efforts to excavate mutant driver factors of metastases in the level of signaling pathways. We introduce two models, EntCDP and ModSDP, to detect the similarity and specificity of pathways in a pan-canc...

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Literature Corpus work: 5d238cd1-0762-5bdc-9361-d09f5830e27d
DOI: 10.1101/2024.11.11.619269

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