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Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms

29 Jan 2019

Abstract excerpt

Being a morning person is a behavioural indicator of a person's underlying circadian rhythm. Using genome-wide data from 697,828 UK Biobank and 23andMe participants we increase the number of genetic loci associated with being a morning person from 24 to 351. Using data from 85,760 individuals with activity-monitor derived measures of sleep timing we find that the chronotype loci associate with sleep timing: the...

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PMID: 30696823
DOI: 10.1038/s41467-018-08259-7

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