Article

Factors influencing the power of polygenic risk score: a survey based on a genotype array dataset of an ulcerative colitis cohort

2022-08-12

Abstract excerpt

<h4>Background: </h4> Polygenic risk scores (PRSs) are personalized assessments based on the cumulative effect of a larger number of genetic variants, and the PRS has been utilized to estimate the risk of a disease or disease-related trait for an individual. However, the capability of PRS can be interfered with by multiple factors spanning from the generating genome-wide association study (GWAS) summary to the PRS...

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Literature Corpus work: 5c7b52e9-b096-5313-bff1-0da1b33549a4
DOI: 10.21203/rs.3.rs-1860757/v1

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