Article
A Polygenic Risk Analysis for Identifying Ulcerative Colitis Patients with European Ancestry.
Genes - 25 May 2024
Liu Ling, Wu Yiming, Li Yizhou, Li Menglong
Abstract excerpt
The incidence of ulcerative colitis (UC) has increased globally. As a complex disease, the genetic predisposition for UC could be estimated by the polygenic risk score (PRS), which aggregates the effects of a large number of genetic variants in a single quantity and shows promise in identifying individuals at higher lifetime risk of UC. Here, based on a cohort of 2869 UC cases and 2900 controls with genotype...
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