Article

An Effective Live Vaccine Strain Of Trypanosoma Cruzi Prevents Chagas Disease In The Mouse Model

2020-10-19

Abstract excerpt

<title>Abstract</title> <italic>Trypanosoma cruzi</italic> is the etiologic agent of Chagas disease for which there are no prophylactic vaccines. Cyclophilin 19 is a secreted cis-trans peptidyl isomerase expressed in all life stages of <italic>Trypanosoma cruzi</italic>, which in the insect stage leads to the inactivation of insect anti-parasitic peptides and parasite transformation and in intracellular amasti...

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Literature Corpus work: 5c48ce24-b6f0-5d94-8543-85f1b70027db
DOI: 10.21203/rs.3.rs-92241/v1

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