Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene-deleted live-attenuated<i>Trypanosoma cruzi</i>parasites as vaccines to protect against Chagas disease

11 Dec 2014

Abstract excerpt

Chagas disease is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi. This illness is now becoming global, mainly due to congenital transmission, and so far, there are no prophylactic or therapeutic vaccines available to either prevent or treat Chagas disease. Therefore, different approaches aimed at identifying new protective immunogens are urgently needed. Live vaccines are likely...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Parasites and Host Interactions
Share to Research on Leishmaniasis Studies
Share to Trypanosoma species research and implications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25496192
DOI: 10.1586/14760584.2015.989989

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene-deleted live-attenuated<i>Trypanosoma cruzi</i>parasites as vaccines to protect against Chagas diseasePMID 25496192Read ↗

Genetically attenuated Trypanosoma cruzi parasites as a potential vaccination tool.Semantic proximity Read ↗

Comparison of antibody and protective immune responses against <i>Trypanosoma cruzi</i> infection elicited by immunization with a parasite antigen delivered as naked DNA or recombinant proteinSemantic proximity Read ↗

Live attenuated Leishmania vaccines: a potential strategic alternativeSemantic proximity Read ↗

Advancement in the Development of DNA Vaccines Against <em>Trypanosoma brucei</em> and Future PerspectiveSemantic proximity Read ↗

Genetically modified live attenuated vaccine: A potential strategy to combat visceral leishmaniasisSemantic proximity Read ↗

Knockout of the dhfr-ts gene in Trypanosoma cruzi generates attenuated parasites able to confer protection against a virulent challenge.Semantic proximity Read ↗

The Immune Response to<i>Trypanosoma cruzi</i>: Role of Toll-Like Receptors and Perspectives for Vaccine DevelopmentSemantic proximity Read ↗

T Cell Specificity: A Great Challenge in Chagas DiseaseSemantic proximity Read ↗

The genetic immunization with paraflagellar rod protein-2 fused to the HSP70 confers protection against late Trypanosoma cruzi infectionSemantic proximity Read ↗

The History of Live Attenuated Centrin Gene-Deleted Leishmania Vaccine CandidatesSemantic proximity Read ↗

A panel of phenotypically and genotypically diverse bioluminescent:fluorescent <i>Trypanosoma cruzi</i> strains as a resource for Chagas disease researchSemantic proximity Read ↗

Exploring the performance of Escherichia coli outer membrane vesicles as a tool for vaccine development against Chagas diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.