Article

Sex differences impact serum metabolome profiles in patients with familial Parkinson’s disease

2026-08-10

Abstract excerpt

Sex differences significantly influence the pathophysiology of Parkinson’s disease (PD). However, it remains unclear whether sex differences affect blood metabolome profiles in patients with PD-related gene mutations compared to healthy controls (HCs). Here, we conducted a 1 H-Nuclear Magnetic Resonance (NMR) metabolomic analysis of serum samples from a defined cohort of patients carrying variants in LRRK2 ( n = 1...

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Literature Corpus work: 5c484a25-afa7-52fe-97e0-ac3d759807fe
DOI: 10.1038/s41531-026-01511-8

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