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Metabolic Profiling of CSF from People Suffering from Sporadic and LRRK2 Parkinson's Disease: A Pilot Study.

Cells - 31 Oct 2020

Yilmaz Ali, Ugur Zafer, Ustun Ilyas, Akyol Sumeyya, Bahado-Singh Ray O, Maddens Michael, Aasly Jan O, Graham Stewart F

Abstract excerpt

CSF from unique groups of Parkinson's disease (PD) patients was biochemically profiled to identify previously unreported metabolic pathways linked to PD pathogenesis, and novel biochemical biomarkers of the disease were characterized. Utilizing both 1H NMR and DI-LC-MS/MS we quantitatively profiled CSF from patients with sporadic PD (n = 20) and those who are genetically predisposed (LRRK2) to the disease (n =...

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Identifiers

PMID: 33142859
DOI: 10.3390/cells9112394
PMCID: PMC7693941

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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