Article

Hypoxia-induced regulation of zDHHC23 opens avenues for new biomarkers for NON MYCN-amplified neuroblastoma

2025-11-04

Abstract excerpt

Neuroblastoma is a highly metastatic paediatric malignancy with poor prognosis, and remains a leading cause of paediatric cancer mortality. Current risk stratification is disproportionately reliant on MYCN amplification, a feature present in only ∼25% of cases. This narrow focus neglects the majority of patients that have non- MYCN amplified tumours, limiting opportunities for therapeutic innovation. To define m...

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Literature Corpus work: 5c18e2d3-7874-5df5-b14d-69c0c6c8f71a
DOI: 10.1101/2025.11.03.686197

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