Article

Dengue virus replicative-form dsRNA is recognized by RIG-I and MDA5 cooperatively to activate innate immunity

2024-10-16

Abstract excerpt

RIG-I like receptors (RLRs) are a family of cytosolic RNA sensors that sense RNA virus infection to activate innate immune response. It is generally believed that different RNA viruses are recognized by either RIG-I or MDA5, two important RLR members, depending on the nature of pathogen-associated molecular patterns (PAMPs) that are generated by RNA virus replication. Dengue virus (DENV) is an important RNA virus...

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Literature Corpus work: 5bdd233f-100d-52cb-bfb2-0c65848dc026
DOI: 10.1101/2024.10.15.618382

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