Article

Elevated levels of Protein S in Multiple Myeloma bone marrow microenvironment regulate tumor progression and bone disease

2024-05-09

Abstract excerpt

<title>Abstract</title> <p>The TAM (TYRO3, AXL, and MERTK) family of receptor tyrosine kinases exhibit cell-transforming capacity promoting tumorigenesis, metastasis and therapy-resistance in various cancer entities. GAS6-MERTK axis represents a target in Multiple Myeloma (MM) to inhibit tumor progression. We sought to explore the role of the alternative TAM receptor ligand Protein S (PROS1) in MM. Whereas <itali...

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Literature Corpus work: 5bc74b7a-97f0-54e0-bdb5-6bcba32ac175
DOI: 10.21203/rs.3.rs-4256896/v1

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