Article

Meningeal neutrophil infiltration drives inflammation-exacerbated pediatric stroke through IL-36γ signaling

2026-04-07

Abstract excerpt

Infection and systemic inflammation have been identified as major risk factors for pediatric stroke; however, the immune mechanisms underlying these clinical observations remain poorly understood. Here, we utilized an LPS-sensitized photothrombotic stroke model (LPS/PT) to investigate the contribution of immune cell infiltration to pediatric stroke pathogenesis and identified a previously unrecognized route of neu...

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Literature Corpus work: 5bb4f89b-47d1-5991-a43c-9cd8ee4a1092
DOI: 10.64898/2026.04.03.716365

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