Article

Targeted RNA-seq improves efficiency, resolution, and accuracy of allele specific expression for human term placentas

2021-01-27

Abstract excerpt

Genomic imprinting is an epigenetic mechanism that results in allele specific expression (ASE) based on parent of origin. It is known to play a role in the prenatal and postnatal allocation of maternal resources in mammals. ASE detected by whole transcriptome RNA-seq (wht-RNAseq) has been widely used to analyze imprinted genes using reciprocal crosses in mice to generate large numbers of informative SNPs. Studies...

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Literature Corpus work: 5b9ad396-cc95-5d73-9138-aea6bb38f660
DOI: 10.1101/2021.01.25.428155

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