Article
Paternally expressed genes predominate in the placenta.
Proceedings of the National Academy of Sciences of the United States of America - 25 Jun 2013
Wang Xu, Miller Donald C, Harman Rebecca, Antczak Douglas F, Clark Andrew G
Abstract excerpt
The discovery of genomic imprinting through studies of manipulated mouse embryos indicated that the paternal genome has a major influence on placental development. However, previous research has not demonstrated paternal bias in imprinted genes. We applied RNA sequencing to trophoblast tissue from reciprocal hybrids of horse and donkey, where genotypic differences allowed parent-of-origin identification of most...
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