Article

The Relationship Between Specific RET Proto-oncogene Mutations and Disease Phenotype in Multiple Endocrine Neoplasia Type 2

1996-11-20

Abstract excerpt

<h3>Objective.</h3> —Multiple endocrine neoplasia type 2 (MEN 2) is an autosomal dominant disorder. The 3 recognized subtypes include MEN 2A, characterized by medullary thyroid carcinoma (MTC), pheochromocytoma (pheo), and hyperparathyroidism (HPT); MEN 2B, by MTC, pheo, and characteristic stigmata; and familial MTC (FMTC), by the presence of MTC only. The purpose of this study was to establish the relationship be...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5b96204c-f288-529f-92e3-50392f683f08
DOI: 10.1001/jama.1996.03540190047028

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Relationship Between Specific RET Proto-oncogene Mutations and Disease Phenotype in Multiple Endocrine Neoplasia Type 2DOI 10.1001/jama.1996.03540190047028Read

The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis.Semantic proximity Read

Does Genotype-Specific Phenotype in Patients with Multiple Endocrine Neoplasia Type 2 Occur as Current Guidelines Predict?Semantic proximity Read

Multiple endocrine neoplasia type 2: evaluation of the genotype-phenotype relationship.Semantic proximity Read

Genotype/phenotype correlations in multiple endocrine neoplasia type 2.Semantic proximity Read

Spectrum of Germline RET Variants Identified by Targeted Sequencing and Associated Multiple Endocrine Neoplasia Type 2 Susceptibility in ChinaSemantic proximity Read

Mutations of the ret protooncogene in German multiple endocrine neoplasia families: relation between genotype and phenotype. German Medullary Thyroid Carcinoma Study GroupSemantic proximity Read

Genotype-phenotype correlation of patients with multiple endocrine neoplasia type 2 in Japan.Semantic proximity Read

Mutations of the ret protooncogene in German multiple endocrine neoplasia families: relation between genotype and phenotype. German Medullary Thyroid Carcinoma Study Group.Semantic proximity Read

Genotype-phenotype relationship in multiple endocrine neoplasia type 2. Implications for clinical management.Semantic proximity Read

Molecular implications of RET mutations for pheochromocytoma risk in multiple endocrine neoplasia 2.Semantic proximity Read

Multiple endocrine neoplasia type 2: 2007 update.Semantic proximity Read

RET proto-oncogene: a review and update of genotype-phenotype correlations in hereditary medullary thyroid cancer and associated endocrine tumors.Semantic proximity Read