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Epigenetic trajectory predicts development of clinical rheumatoid arthritis in anti-citrullinated protein antibody positive individuals: Targeting Immune Responses for Prevention of Rheumatoid Arthritis (TIP-RA)

2024-10-16

Abstract excerpt

The presence of anti-citrullinated protein antibodies (ACPAs) in the absence of clinically-apparent inflammatory arthritis (IA) identifies individuals “at-risk” for developing future clinical rheumatoid arthritis (RA). However, it is unclear why some ACPA+ individuals convert to clinical RA while others do not. We explored the possibility that epigenetic remodeling is part of the trajectory from an at-risk state t...

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Literature Corpus work
5b6cea6f-8c4e-588b-89e9-c8e02c56793a
DOI
10.1101/2024.10.15.618490
Open publication

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Epigenetic trajectory predicts development of clinical rheumatoid arthritis in anti-citrullinated protein antibody positive individuals: Targeting Immune Responses for Prevention of Rheumatoid Arthritis (TIP-RA)DOI 10.1101/2024.10.15.618490
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