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Article

Zerumbone ameliorates behavioral impairments and neuropathology in transgenic APP/PS1 mice by suppressing MAPK signaling

2020-02-03

Abstract excerpt

<title>Abstract</title><p>Background : Alzheimer’s disease (AD) is a major clinical problem, but there is a distinct lack of effective therapeutic drugs for this disease. We investigated the potential therapeutic effects of zerumbone, a subtropical ginger sesquiterpene, in transgenic APP/PS1 mice, rodent models of AD which exhibit cerebral amyloidosis and neuroinflammation. Methods : The N9 microglial cell line an...

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Literature Corpus work
5b41d07c-bab6-5499-bf7e-2dbf538b7ca3
DOI
10.21203/rs.2.17060/v2
Open publication

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Zerumbone ameliorates behavioral impairments and neuropathology in transgenic APP/PS1 mice by suppressing MAPK signalingDOI 10.21203/rs.2.17060/v2
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