Article
Protective effects of ginkgolide on a cellular model of Alzheimer’s disease via suppression of the NF-κB signaling pathway
2021-08-13
Abstract excerpt
NF-κB signaling has been reported to play a key regulatory role in the pathogenesis of Alzheimer’s disease (AD). The purpose of this study is to investigate the effects of ginkgolide on cell viability in an AD cellular model involving an APP/PS1 double gene-transfected HEK293 cell line (APP/PS1-HEK293) and further explored the mechanisms of action related to NF-κB signaling. The optimal time point and concentratio...
Topics
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- Alzheimer's disease research and treatments
- Cholinesterase and Neurodegenerative Diseases
- Flavonoids in Medical Research
- Ginkgo biloba and Cashew Applications
- Neurological Disease Mechanisms and Treatments
- Phytochemicals and Antioxidant Activities
- Phytoestrogen effects and research
- Tryptophan and brain disorders
Identifiers and source
- Literature Corpus work
- 40cac2d9-ce84-5f2f-8470-6222338afd28
- DOI
- 10.21203/rs.3.rs-791848/v1
