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Article

Epigenetic regulation of epithelial dectin-1 through an IL-33-STAT3 axis in allergic disease

2020-11-01

Abstract excerpt

Allergic diseases arise in susceptible individuals in part because of decrements in protective pathways. The mechanism by which these anti-inflammatory molecules become repressed remains unclear. We have previously reported that epithelial dectin-1 prevents aberrant type 2 responses and is downregulated in the epithelium of allergic patients. Here we report that dectin-1 is constitutively expressed by the respirat...

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Identifiers and source

Literature Corpus work
5b3122cf-1e6c-54af-9624-972781a57768
DOI
10.1101/2020.11.01.364067
Open publication

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Epigenetic regulation of epithelial dectin-1 through an IL-33-STAT3 axis in allergic diseaseDOI 10.1101/2020.11.01.364067
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