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Article

Epigenetic regulation of epithelial dectin‐1 through an IL‐33‐STAT3 axis in allergic disease

13 May 2021

Abstract excerpt

Allergic diseases arise in susceptible individuals in part because of decrements in protective pathways. The mechanism by which these anti-inflammatory molecules become repressed remains unclear. We have previously reported that epithelial dectin-1 prevents aberrant type 2 responses and is downregulated in the epithelium of allergic patients. Here, we report that dectin-1 is constitutively expressed by the...

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PMID: 33982290
DOI: 10.1111/all.14898

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