Article

Cardiac fibroblast GSK-3α mediates adverse myocardial fibrosis via IL-11 and ERK pathway

2021-02-02

Abstract excerpt

<h4>Background</h4> Heart failure is the leading cause of mortality, morbidity, and healthcare expenditures worldwide. Numerous studies have implicated Glycogen Synthase Kinase-3 (GSK-3) as a promising therapeutic target for cardiovascular diseases. GSK-3 isoforms appear to play overlapping, unique, and even opposing functions in the heart. Recently our group has identified cardiac fibroblast (CF) GSK-3β as a neg...

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Literature Corpus work: 5b28b072-4ce3-5d60-b23f-ef9bdf1ba59c
DOI: 10.1101/2021.02.02.429435

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