Article

Hypothalamic A11 Nuclei Regulate the Circadian Rhythm of the Mechanonociception and the Spinal Clock Gene Transcription through Dopamine Receptor Activation

2020-09-08

Abstract excerpt

Patients with degenerative diseases refer to feeling more pain during the night. However, it is unknown whether spinal nociception can be circadian and how is it controlled. We investigated whether the paw withdrawal threshold (PWT) could exhibit physiological circadian behavior as well as the contribution of the dopaminergic A11 nucleus and the spinal dopamine (DA) receptors (DRs) on the circadian PWT and the spi...

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Literature Corpus work: 5b062e07-fce9-52d3-bc40-07244e282a0b
DOI: 10.20944/preprints202009.0188.v1

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