Article
Calcitonin receptors are ancient modulators for rhythms of preferential temperature in insects and body temperature in mammals.
Genes & development - 15 Jan 2018
Goda Tadahiro, Doi Masao, Umezaki Yujiro, Murai Iori, Shimatani Hiroyuki, Chu Michelle L, Nguyen Victoria H, Okamura Hitoshi, Hamada Fumika N
Abstract excerpt
Daily body temperature rhythm (BTR) is essential for maintaining homeostasis. BTR is regulated separately from locomotor activity rhythms, but its molecular basis is largely unknown. While mammals internally regulate BTR, ectotherms, including Drosophila, exhibit temperature preference rhythm (TPR) behavior to regulate BTR. Here, we demonstrate that the diuretic hormone 31 receptor (DH31R) mediates TPR during the...
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