Article

An Innovative Data Analysis Strategy For Accurate NGS Detection of Tumor mtDNA Mutations

2020-07-23

Abstract excerpt

<h4>Background: </h4> Next generation sequencing (NGS) technology has been commonly applied to detect mtDNA mutations, which are reported to be strongly associated with cancers. However, several key challenges still exist in the bioinformatic analysis of mtDNA sequencing data, which greatly affect the detection accuracy of mtDNA mutations. <h4>Methods: </h4>: Here, we systematically evaluated several key analysis...

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Literature Corpus work: 5af73a61-e10e-5b9d-bf38-c1b3453152bc
DOI: 10.21203/rs.3.rs-46773/v1

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