Article

Antigenic mimicry by Akkermansia muciniphila drives IgA nephropathy

2026-06-08

Abstract excerpt

<title>Abstract</title> <p>Immunoglobulin A nephropathy (IgAN), defined by mesangial IgA deposition, is the most common primary glomerulonephritis worldwide and remains a major global health challenge. Although IgAN pathogenesis clearly involves galactose-deficient IgA1 (Gd-IgA1) inducing autoantibody generation and subsequent kidney immune complex deposition, the upstream immunological triggers that initiate and...

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Literature Corpus work: 5ae8fe99-e68e-54af-b8fc-15938c728b4e
DOI: 10.21203/rs.3.rs-9873170/v1

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