Article

Molecular signatures associated with ZIKV exposure in human cortical neural progenitors

2016-08-23

Abstract excerpt

Zika virus (ZIKV) infection causes microcephaly and has been linked to other brain abnormalities. How ZIKV impairs brain development and function is unclear. Here we systematically profiled transcriptomes of human neural progenitor cells exposed to Asian ZIKV C , African ZIKV M , and dengue virus (DENV). In contrast to the robust global transcriptome changes induced by DENV, ZIKV has a more selective and larger...

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Literature Corpus work: 5aca594e-5bc4-5ae5-a4e0-b21f81b72d90
DOI: 10.1101/071183

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