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Article

Molecular signatures associated with ZIKV exposure in human cortical neural progenitors

31 Aug 2016

Abstract excerpt

linked to other brain abnormalities. How ZIKV impairs brain development and function is unclear. Here we systematically profiled transcriptomes of human neural progenitor cells exposed to Asian ZIKV C , African ZIKV M , and dengue virus (DENV). In contrast to the robust global transcriptome changes induced by DENV, ZIKV has a more selective and larger impact on expression of genes involved in DNA replication and...

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PMID: 27580721
DOI: 10.1093/nar/gkw765

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