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Article

Differential Responses of Human Fetal Brain Neural Stem Cells to Zika Virus Infection

16 Feb 2017

Abstract excerpt

Zika virus (ZIKV) infection causes microcephaly in a subset of infants born to infected pregnant mothers. It is unknown whether human individual differences contribute to differential susceptibility of ZIKV-related neuropathology. Here, we use an Asian-lineage ZIKV strain, isolated from the 2015 Mexican outbreak (Mex1-7), to infect primary human neural stem cells (hNSCs) originally derived from three individual...

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Mosquito-borne diseases and control
Viral Infections and Vectors
Virology and Viral Diseases

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28216147
DOI: 10.1016/j.stemcr.2017.01.008

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