Article

Combined proteome and transcriptome analyses reveal that Zika virus circulating in Brazil alters cell cycle and neurogenic programmes in human neurospheres

2016-05-09

Abstract excerpt

Zika virus (ZIKV) has been associated with microcephaly and other brain abnormalities; however, the molecular and cellular consequences of Zika virus circulating in Brazil to the human brain development have not been studied yet. Here we describe alterations in human neurospheres derived from neural stem cells infected with Brazilian ZIKV. Combined proteomics and mRNA transcriptional profile analyses showed that B...

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Literature Corpus work: 972cc36f-dc98-56de-a6ed-b1cfffed1fc7
DOI: 10.7287/peerj.preprints.2033v1

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