Article

Soluble Guanylate Cyclase Reduced the Gastrointestinal Fibrosis in Bleomycin-induced Mouse Model of Systemic Sclerosis.

2021-01-05

Abstract excerpt

<h4>Background: </h4> Systemic sclerosis (SSc) is a chronic autoimmune-mediated connective tissue disorder. Although the etiology of the disease remains undermined, SSc is characterized by fibrosis and proliferative vascular lesions of the skin and internal organs. SSc involves the gastrointestinal tract in more than 90% of patients. Soluble guanylate cyclase (sGC) is used to treat pulmonary artery hypertension (P...

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Literature Corpus work: 59eba3f5-ece2-581c-98b3-492d62ac8868
DOI: 10.21203/rs.3.rs-138442/v1

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