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Article

Chondroitin sulfate prevents peritoneal fibrosis in mice by suppressing NF-κB activation.

Medical molecular morphology - 1 Sept 2016

Abe Shinichi, Obata Yoko, Oka Satoru, Koji Takehiko, Nishino Tomoya, Izumikawa Koichi

Abstract excerpt

Long-term peritoneal dialysis causes peritoneal fibrosis, and previous reports suggest that inflammation plays a critical role in peritoneal fibrosis. Chondroitin sulfate (CS) suppresses the inflammatory response by preventing activation of nuclear factor (NF)-κB. We examined the effect of CS on the peritoneal fibrosis induced by chlorhexidine gluconate (CG) in mice. CS or water was administered daily. We divided...

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PMID: 26880269
DOI: 10.1007/s00795-016-0133-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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