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Article

Ihha induces hybrid cartilage-bone cells during zebrafish jawbone regeneration

1 Jan 2016

Abstract excerpt

The healing of bone often involves a cartilage intermediate, yet how such cartilage is induced and utilized during repair is not fully understood. By studying a model of large-scale bone regeneration in the lower jaw of adult zebrafish, we show that chondrocytes are crucial for generating thick bone during repair. During jawbone regeneration, we find that chondrocytes co-express genes associated with osteoblast...

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PMID: 27122168
DOI: 10.1242/dev.131292

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