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Article

Low frequency stimulation decreases seizure activity in a mutation model of epilepsy.

Epilepsia - 1 Sept 2010

Kile Kara Buehrer, Tian Nan, Durand Dominique M

Abstract excerpt

PURPOSE: To investigate brain electrical activity in Q54 mice that display spontaneous seizures because of a gain-of-function mutation of the Scn2a sodium channel gene, and to evaluate the efficacy of low frequency deep brain stimulation (DBS) for seizure frequency reduction. METHODS: Electroence...

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Identifiers

PMID: 20659150
DOI: 10.1111/j.1528-1167.2010.02679.x
PMCID: PMC3569726

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20659150-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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