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Article

Novel senolytic and senescence-suppressing compounds overcome senescence-driven chemoresistance in NSCLC

2026-08-20

Abstract excerpt

<title>Abstract</title> <p> <underline>Background</underline> Non-small cell lung cancer (NSCLC) is characterized by a high recurrence rate after curative resection of early-stage disease and a poor overall survival. Although targeted therapy and immunotherapy have reshaped the standard-of-care (SOC) of NSCLC, chemotherapy, particularly platinum-doublet regimens, remains a key treatment modality in early-stage,...

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Literature Corpus work
59a13f95-34b8-5c6b-b637-d4f36c806b46
DOI
10.21203/rs.3.rs-10535379/v1
Open publication

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Novel senolytic and senescence-suppressing compounds overcome senescence-driven chemoresistance in NSCLCDOI 10.21203/rs.3.rs-10535379/v1
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