Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeting senescence as an anticancer therapy

6 Sept 2022

Abstract excerpt

Cellular senescence is a stress response elicited by different molecular insults. Senescence results in cell cycle exit and is characterised by multiple phenotypic changes such as the production of a bioactive secretome. Senescent cells accumulate during ageing and are present in cancerous and fibrotic lesions. Drugs that selectively kill senescent cells (senolytics) have shown great promise for the treatment of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced biosensing and bioanalysis techniques
Share to Epigenetics and DNA Methylation
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36065138
DOI: 10.1002/1878-0261.13312

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeting senescence as an anticancer therapyPMID 36065138Read ↗

Targeting senescent cells: approaches, opportunities, challengesSemantic proximity Read ↗

The Jekyll and Hyde of Cellular Senescence in CancerSemantic proximity Read ↗

Strategies targeting cellular senescenceSemantic proximity Read ↗

Cellular Senescence: The Sought or the Unwanted?Semantic proximity Read ↗

Targeting Senescence: A Review of Senolytics and Senomorphics in Anti-Aging InterventionsSemantic proximity Read ↗

The dual role of cellular senescence in human tumor progression and therapySemantic proximity Read ↗

Regulation of cellular senescence in tumor progression and therapeutic targeting: mechanisms and pathwaysSemantic proximity Read ↗

Cellular senescence: a key therapeutic target in aging and diseasesSemantic proximity Read ↗

Targeting cellular senescence with senotherapeutics: senolytics and senomorphicsSemantic proximity Read ↗

Senescent Cells in Cancer: Wanted or Unwanted CitizensSemantic proximity Read ↗

Cellular Senescence: A Translational Perspective.Semantic proximity Read ↗

Escape from senescence: molecular basis and therapeutic ramificationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.