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The Potential of Senescence as a Target for Developing Anticancer Therapy.

International journal of molecular sciences - 8 Feb 2023

Jo Hyein, Shim Kyeonghee, Jeoung Dooil

Abstract excerpt

Senescence occurs in response to various stimuli. Senescence has attracted attention because of its potential use in anticancer therapy as it plays a tumor-suppressive role. It also promotes tumorigeneses and therapeutic resistance. Since senescence can induce therapeutic resistance, targeting senescence may help to overcome therapeutic resistance. This review provides the mechanisms of senescence induction and...

Topics

Humans
Cellular Senescence
Phenotype
Neoplasms
Carcinogenesis
Cell Proliferation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36834846
DOI: 10.3390/ijms24043436
PMCID: PMC9961771

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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