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A Network Approach to Identify Biomarkers of Differential Chemotherapy Response Using Patient-Derived Xenografts of Triple-Negative Breast Cancer

2021-08-20

Abstract excerpt

<h4>Summary</h4> Triple negative breast cancer (TNBC) is a highly heterogeneous set of diseases that has, until recently, lacked any FDA-approved, molecularly targeted therapeutics. Thus, systemic chemotherapy regimens remain the standard of care for many. Unfortunately, even combination chemotherapy is ineffective for many TNBC patients, and side-effects can be severe or lethal. Identification of predictive biom...

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Literature Corpus work
f34917af-7b2c-5d8e-b748-f0113042fa36
DOI
10.1101/2021.08.20.457116
Open publication

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A Network Approach to Identify Biomarkers of Differential Chemotherapy Response Using Patient-Derived Xenografts of Triple-Negative Breast CancerDOI 10.1101/2021.08.20.457116
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