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Priming of MSCs with inflammation-relevant signals affects extracellular vesicle biogenesis, surface markers, and modulation of T cell subsets

2020-05-02

Abstract excerpt

Although considerable evidence exists supporting the use of mesenchymal stromal cells (MSCs) for treating immune diseases, successful clinical translation has been challenging and has led researchers to investigate cell-free alternatives. MSC-derived extracellular vesicles (MSC-EVs) have been shown to mediate a significant portion of the observed therapeutic effect, including immunosuppression. MSCs have been show...

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Literature Corpus work
594ce4f4-67ab-5f75-90d0-6977821663a9
DOI
10.1101/2020.04.30.066456
Open publication

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Priming of MSCs with inflammation-relevant signals affects extracellular vesicle biogenesis, surface markers, and modulation of T cell subsetsDOI 10.1101/2020.04.30.066456
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