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Analysis of Structural Variation Among Inbred Mouse Strains Identifies Genetic Factors for Autism-Related Traits

2021-02-18

Abstract excerpt

The genomes of six inbred strains were analyzed using long read (LR) sequencing. The results revealed that structural variants (SV) were very abundant within the genome of inbred mouse strains (4.8 per gene), which indicates that they could impact genetic traits. Analysis of the relationship between SNP and SV alleles across 53 inbred strains indicated that we have a very limited ability to infer whether SV are pr...

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Literature Corpus work
58c63967-9c0e-5895-894c-6077aee4076b
DOI
10.1101/2021.02.18.431863
Open publication

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Analysis of Structural Variation Among Inbred Mouse Strains Identifies Genetic Factors for Autism-Related TraitsDOI 10.1101/2021.02.18.431863
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