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Benchmarking DNA Foundation Models for Genomic and Genetic Tasks

2024-08-18

Abstract excerpt

The rapid evolution of DNA foundation models promises to revolutionize genomics, yet comprehensive evaluations are lacking. Here, we present a comprehensive, unbiased benchmark of five models (DNABERT-2, Nucleotide Transformer V2, HyenaDNA, Caduceus-Ph, and GROVER) across diverse genomic and genetic tasks including sequence classification, gene expression prediction, variant effect quantification, and topologicall...

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Literature Corpus work
93607212-4fa2-56c9-9a1d-c1d1b05afd52
DOI
10.1101/2024.08.16.608288
Open publication

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Benchmarking DNA Foundation Models for Genomic and Genetic TasksDOI 10.1101/2024.08.16.608288
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